Plasmolifting – the use of platelet membranes from blood plasma in dentistry

Gum pathologies progress quite quickly, affecting the deep layers of soft tissue. Previously, treatment took a long time, and the patient had to visit the doctor frequently. A modern technique, plasmolifting of the gums, allows you to eliminate pathological conditions almost immediately.

The Otradnoe clinic is equipped with licensed equipment, and doctors specialize in the treatment of dental diseases of any complexity, so if you have questions or need to have gum plasma lifting in Moscow, make an appointment with a doctor at any time convenient for you.

Plasmolifting and its application in dentistry

Today, with the help of the latest “ plasmolifting ” technology in dental practice, you can get rid of bleeding gums and bad breath, and accelerate the regenerative capabilities of body tissues after surgery. The technique is actively widespread and used in many medical fields, and since 2004 it has been developed in dentistry. The founders of the technique are maxillofacial surgeons from Russia Roman Zarudiy and Renat Akhmerov.

The basis of the technique is the use of plasma produced from the patient’s own blood. The peculiarity of the procedure lies in the materials used. Blood plasma, saturated with a large number of platelets and protein cells, is otherwise called autoplasma. The material is produced in a laboratory by centrifuging blood in a special apparatus. High installation speeds separate the blood into components, the main value of which is platelets. These blood elements are responsible for regeneration and protective function in the body. Platelet autoplasma activates the regenerative potential of dental tissues and mucous membranes, reduces inflammatory processes, and enhances local immunity of the oral cavity. The effectiveness and harmlessness of the technique lies in the relationship at the biological level, as well as the complete compatibility of the components with the patient’s cells.

Along with this technique, membranes from blood plasma are used, which are implanted simultaneously with implants and enhance regenerative processes. The use of a membrane increases the rate of tissue recovery, minimizes bleeding and the likelihood of non-engraftment of the structure, and the likelihood of suture dehiscence becomes significantly less.

Plasmolifting of the gums is also used - an innovative technology for the treatment and restoration of periodontal tissues. The technique has its full name – “platelet-rich fibrin”. At the moment, the technology is dynamically used both for working with periodontium and during implant installation operations. The resulting concentrate is injected into the bone cavity where the implant will be implanted, or into the hole after the extracted tooth.

What is the effect of plasmolifting gums

• Relieves bad breath
• Eliminates bleeding
• Reduces tooth mobility
• Restores gum color and structure
• Accelerates the healing process
• Relieves inflammation
• Reduces the risk of implant rejection
• Strengthens bone tissue

Plasmolifting in the complex treatment of periodontal diseases is carried out after professional hygiene and relief of acute inflammation.

What is platelet fibrin

Human blood contains formed elements, one of which is transparent, anucleate cells - platelets. They take part in the process of blood clotting and stopping bleeding. During the destruction of the walls of a blood vessel, platelets, disintegrating, release components that form blood clots. In the 80s, an effective function was discovered: to increase the rate of healing and tissue restoration. This process occurs due to the release of growth factors (hormonal components) that enhance the regeneration of old cells, as well as the growth and increase in the number of new cells.

Platelet autoplasma is not only formed elements, but also saturated platelet fibrin. This is a yellowish liquid released when blood is processed in a special centrifuge.

It contains:

• platelets;
• fibrin;
• fats;
• hormones;
• nucleic acids;
• mineral components.

After the autoplasma is introduced into the jaw bone, growth factors are activated within a week. The tissues are intensively saturated with oxygen, and a dense capillary network is formed. The rate of restoration of jaw bone cells and their growth, as well as tissue nutrition, increases.

Human autoplasma is saturated with nutrients and is biocompatible with the body, because it is its own product. Consequently, engraftment is successful and side effects never develop. The restoration is proceeding as planned.

Operating principle

Biological material is administered by pinpoint injection into the affected areas of the gums. After the autoplasma enters the tissue structures, the active action of the biocomponents begins.

The principle of the procedure is based on the targeted activation of tissue regeneration at the cellular level. The therapeutic effect is achieved thanks to the unique composition of the biomaterial. During the separation of autoplasma from plasma cells, it is additionally saturated with platelets. To control the normalization of blood clotting, heparin is added to the material. The finished plasma, saturated with useful elements, comes into contact with tissue structures and improves their vital functions.

The role of platelets is to stop bleeding. When tissues are injured, they rush to the edges of the wound, creating a kind of protective barrier that prevents blood loss. In this way, natural restoration of damaged tissue occurs.

The advantages of the procedure include high efficiency, preservation of the therapeutic result for a long time, safety and painlessness.

Our team of doctors

Maxillofacial surgeon, Implantologist

Bocharov Maxim Viktorovich

Experience: 11 years

Orthopedist, Neuromuscular dentist

Stepanov Andrey Vasilievich

Experience: 22 years

Orthopedic dentist

Tsoi Sergey Konstantinovich

Experience: 19 years

Endodontist, Therapist

Skalet Yana Alexandrovna

Experience: 22 years

Endodontist, Therapist, Orthopedist

Varvyanskaya Anastasia Andreevna

Experience: 6 years

Dentist-orthodontist

Enikeeva Anna Stanislavovna

Experience: 3 years

Possible alternatives

Plasmolifting refers to maintenance therapy that inhibits the development of periodontitis if the patient follows all the doctor’s instructions. Among the alternatives, you can consider curettage of the gums, but it only removes plaque from under the mucous membranes. Treatment with Vector and Varius devices also works in a similar way - they only remove deposits, but do not nourish the gums.

In the treatment of diseases, injections with antibiotics can also be performed, but they are not suitable for all patients, and they also have a very short-lived effect. A “shock” dose of vitamin C has a good effect on the condition of the mucous membranes, but, firstly, many patients are allergic to it, and secondly, to achieve the best effect, it is better to combine several approaches at once and carry out complex treatment. Therefore, in essence, plasma lifting today has no alternatives in terms of restoring healthy gums.

1 Achkasov E.E., Bezuglov E.N., Ulyanov A.A., Kurshev V.V., Repetyuk A.D., Egorova O.N. Application of autoplasma enriched with platelets in clinical practice. Biomedicine, 2013.

Indications and contraindications for the use of plasma lifting

Indications:

• increasing the rate of tissue healing during sinus surgery and bone addition;
• recession plastic;
• treatment of periodontal diseases;
• activation of growth factors in bone cells after tooth extraction;
• implantation simultaneously with the introduction of bone material;
• various surgical interventions.

Contraindications:

• malignant neoplasms;
• systemic diseases of the blood system that do not allow plasma to be isolated or used effectively;
• decreased immunity;
• diseases in the acute stage;
• taking antibiotics;
• mental illness.

Contraindications

Relative contraindications include hepatitis and infectious diseases - pneumonia, botulism, typhoid fever, fever and others. With such pathologies, the composition of the blood tends to change quickly, so plasma lifting is impossible. It is carried out only after the diseases have been eliminated.

It is strictly forbidden to administer autoplasma injections for malignant neoplasms in any organ, HIV and pathologies of the circulatory system. Also, the procedure is not performed in case of allergic reactions to heparin, which is part of the biomaterial.

Benefits of using blood plasma

The introduction of a platelet membrane naturally activates cellular growth factors of the jaw bone and periodontal tissues, increasing the rate of recovery. Regeneration and acceptance of implants or bone material by the body is much faster, and the likelihood of inflammation is significantly minimized.

Blood plasma membranes have a positive effect on:

• increase in the rate of cellular growth factor in the bone after implantation;
• absence of allergies that could occur when interacting with foreign materials;
• accelerated gum recovery after implantation or plastic surgery;
• prevention of inflammation around the implant;
• reduction of swelling and pain after surgical procedures;
• optimal tightening of the socket after tooth extraction;
• minimizing inflammation during gingival curettage and cleaning periodontal pockets.

When else is plasma lifting used?

Very often, plasma lifting is used during various traumatic manipulations. These include:

1. Installation of implants.
2. Open sinus lift.
3. Closed sinus lift.
4. Bone block grafting.
5. Splitting of the alveolar ridge.
6. Tooth extraction.

That is, the technique can be used after surgical operations that are accompanied by large incisions of the gums, isolation of bone fragments and installation of artificial roots. In such cases, plasma lifting will help to quickly restore the capillary network and speed up the process of tissue regeneration, which will ultimately shorten the recovery period.

Preparation for plasma lifting

To carry out the innovative dental method of plasma lifting at a reasonable price, Implantmaster in Moscow has all the necessary latest equipment. Before carrying out medical manipulations, a thorough visual and instrumental examination of the oral cavity is carried out at the consultation. Next, the specialist will order an x-ray.

We perform cone beam computed tomography. The pictures are more accurate, and the Rg radiation is even less. Thanks to this, the most accurate diagnosis can be made.

Our doctors use a Labomed Magna dental microscope to thoroughly examine the condition of teeth and surrounding tissues. An examination is also carried out to determine contraindications to surgery. If no contraindications are identified, then a treatment plan is drawn up.

The doctor answers all the patient’s questions. He explains in detail the surgical procedure and schedules an appointment. To undergo the procedure as comfortably and correctly as possible, you should perform preparatory measures before performing plasma lifting:

• pre-carry out professional cleaning of the oral cavity;
• 7 days before the procedure you should not drink alcohol, heavy and spice-rich foods, or hot drinks;
• minimize smoking;
• increase the amount of water consumption to 2 liters per day;
• before treatment, do not take painkillers and drugs that affect blood clotting;
• Do not eat before the procedure.

These recommendations will allow you to carry out the upcoming procedure most effectively. And after the operation, you must follow all the specialist’s instructions.

Features of the procedure

Plasmolifting is absolutely harmless, since the components of blood plasma are natural to humans. This is an individual product of “personal production”, which is 100% likely to be perceived positively by the body. The technique has virtually no contraindications. Used in the following cases:

• for the prevention of gum pathologies;
• for gingivitis, periodontal disease, periodontitis;
• after complex dental surgical interventions (implantation, extraction of complex teeth);
• for bleeding, inflammation of the gums;
• to eliminate unsteadiness and excessive sensitivity of units.

After plasma lifting, you will not have to take antibiotics and anti-inflammatory drugs, since the procedure removes not only the symptoms, but also the causes of periodontal disease. Contraindications include only serious systemic pathologies affecting blood quality:

• HIV;
• hepatitis;
• acute infections, inflammatory pathologies;
• hormonal imbalance;
• allergy to heparin.

Plasmapheresis - obtaining a membrane from blood plasma

For the plasmapheresis procedure, not blood from a vein is used, but plasma from centrifuged blood. When injecting autoplasma, the tissues of the oral mucosa are saturated with nutrients. The material is otherwise referred to as “platelet-rich plasma” containing platelet concentrate.

Effectiveness is ensured by plasma with a large number of platelets in 1 μl. To achieve such saturation of the biomaterial, plasmapheresis is necessary.

1. Up to 20 ml of blood is drawn from the patient's elbow.

2. To separate the blood into its constituent components and separate unnecessary elements, it is centrifuged twice in a test tube for 15 minutes.

3. The necessary components are removed - plasma and fibrin clot.

Platelets, fibrin and biologically active substances are saturated, transforming into autoplasma. An injection is given into the marginal gum, interdental papilla or gingival projection of the tooth root.

Also, the remaining fibrin clot (membrane from blood plasma) is used for surgical interventions - osteoplasty, stimulating the healing of the hole. The shelf life of the membrane is no more than a few hours. Plasmapheresis is performed exclusively on the day of surgery. Our specialists have all the knowledge and skills to ensure technically complex operations.

Advantages of plasma lifting

Main advantages:

1. Safety – when using a biomaterial that is completely compatible with the patient’s body, rejection is excluded, and allergic reactions are excluded. The procedure is performed under sterile conditions, so the risk of infection is also minimal.
2. Assistance in rehabilitation and recovery after various surgical dental procedures. Plasma injections can significantly reduce tissue healing time after complex tooth extraction, implant installation, or gum incision.
3. Painless and time saving - the whole procedure takes no more than 10 minutes. In rare cases, discomfort may occur, but in general the injection is not painful.
4. Improving the aesthetic appearance of the oral cavity. After plasma lifting, inflammation, bleeding and swelling of the gums go away.

The effectiveness of the procedure can be fully assessed 1-2 weeks after the injection of plasma into the gum tissue.

The use of membranes to add bone, during implantation, and also after tooth extraction

At Implantmaster, all surgical interventions are performed under pain relief using anesthesia. Our specialists perform atraumatic removal of all teeth, even multi-rooted ones.

The maxillofacial surgeon, implant surgeon, in order to prevent breakage of the partition between the roots, separates them from each other. Using a periotome, the marginal gum is gently moved away from the tooth to preserve its integrity. Next, using an innovative piezo scalpel - the VarioSurg LED ultrasonic surgical system from NSK (made in Japan) - the roots are separated and their subsequent segmentation is carried out. Removal becomes safe, painless and as comfortable as possible for the patient. Ultrasound manipulation has an antiseptic effect and in the future you can do without taking antibiotics. The risk of infection and complications in the oral cavity is reduced. Immediately after ultrasound exposure, it can be implanted. Our highly qualified specialists use the latest materials and technologies, such as Straumann or Osstem implants. Their osteointegration takes place in 3-5 weeks, and they can also be installed when the bone level is small.

Subsequent application of platelet membranes containing cell growth factors accelerates regeneration. During surgery, the membrane covers the defect, implanted bone material or artificial root. Sometimes a fibrin clot is combined with the patient's bone material and introduced into the defect area. Afterwards, suture material is applied.

If the membrane was installed to prevent alveolar inflammation after removal, then sutures are not applied. It is not advisable to rinse your mouth during the first 3 days.

How to prepare for the procedure?

There are certain indications for the procedure. First of all, they relate to any inflammatory (infectious, bacterial) processes in the body - they should not exist. Roughly speaking, the patient’s blood must be clean - only in this case the injections will really be effective. Therefore, before a course of plasma lifting, a clinical blood test must be taken, which will show the absence/presence of inflammatory processes.

It is better to schedule the procedure itself in the morning, since before it you cannot eat for at least 4 hours (you can and even need to drink, but only water). 2-3 days before treatment, you must avoid fatty and spicy foods and avoid alcohol. It is necessary to understand that the procedure is carried out in a course, therefore, during the entire period of treatment it is necessary to adhere to a similar diet.

Certified doctors! Specialists who have been trained in the use of plasma lifting in dentistry. We know, we can and we achieve high treatment results!

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Recommendations after plasma lifting

Plasmolifting is carried out in combination with other medical procedures. The duration of the rehabilitation period is determined depending on the disease and the medical procedures performed.

Recommendations for the patient to follow after treatment:

• limit physical activity during the recovery period;
• avoid exposure to high and low temperatures - baths, saunas, solariums;
• do not disturb the intervention site with your tongue and brush;
• maintain proper oral hygiene;
• temporarily eliminate hard and irritating foods and alcohol consumption.

Plasmolifting in the treatment of periodontitis

Periodontitis is an inflammatory disease of the gums, a complication of gingivitis. In addition to inflammation and bleeding gums, symptoms such as the formation of periodontal pockets and tooth mobility are observed. The more severe periodontitis is, the more pronounced these symptoms will be. Treatment of periodontitis is always comprehensive and includes mandatory removal of dental plaque, sanitation of the oral cavity, and anti-inflammatory therapy. In the most severe cases, surgical treatment is used. Plasmolifting is used for the complex treatment of mild to moderate periodontitis. In severe cases of the disease, surgical methods are prescribed, but plasma lifting can also be used to increase the effectiveness of treatment and accelerate tissue recovery.

What is the result?

The patient will notice clear improvements in the condition immediately after the procedure.

Within a few days:

• The unpleasant odor disappears;
• Stop bleeding gums;
• The holes heal quickly after removal.

Plasmolifting also blocks the development of periodontal disease and promotes implant healing.

To obtain the desired result, experts recommend repeating the procedure 3-4 times, which depends on the diagnosis and condition of the patient. In standard cases, plasma is administered once a week for a month or more. The course is repeated every three or six months.

Forecast

Of course, many patients are interested in the question of how plasma lifting “works” and what positive trends will be observed during the treatment process. The process, starting from the moment of injection and ending with the recovery of the affected area, is as follows:

1. Injection administration.
2. Integration of protein cells and platelets into the affected area.
3. Interaction with natural proteins.
4. Activation of the body’s immune processes (a decrease in the symptoms of the disease and accelerated tissue healing are observed).
5. Regeneration of damaged areas and disappearance of painful symptoms.

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Indications

Indications for which the use of plasma lifting is permitted include the following conditions:

1. Generalized periodontitis of three degrees of severity.
2. Localized periodontitis.
3. Gingivitis and alveolitis.
4. Operations related to removal and implantation .
5. Peri-implantitis.
6. Preventive measures against periodontal tissue diseases.

Reviews

Reviews from patients can speak eloquently about the effectiveness of dental plasma lifting. They allow you to evaluate the advantages and disadvantages and draw your own conclusions regarding the effectiveness of this treatment method.

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